Dear Colleagues,
It is a pleasure to invite you to the Special Issue in Cells entitled:
“NF-κB Signaling in Inflammation: Molecular Mechanisms and Therapeutic Targets.”
The international journal Cells, an open-access journal indexed in PubMed, has launched a Special Issue dedicated to the role of the NF-κB signaling pathway in inflammatory processes, with a particular focus on molecular mechanisms and potential therapeutic applications.
NF-κB is a key regulator of immune and inflammatory responses, cell survival, and tissue homeostasis. Aberrant activation of NF-κB signaling is involved in numerous acute and chronic diseases, including cancer. Despite decades of research, NF-κB continues to emerge as a highly dynamic signaling system that is strongly dependent on the biological context.
Cosa troverete nello Special Issue:
This Special Issue aims to provide an up-to-date overview of recent advances in the study of NF-κB signaling, including:
- Canonical and non-canonical NF-κB pathways
- Upstream signaling events
- Post-translational modifications
- Interactions with other signaling pathways
- Development of pharmacological or biological strategies targeting components of the NF-κB pathway
- New perspectives on the molecular mechanisms controlling NF-κB activation
- Innovative studies on the role of the pathway in inflammatory and chronic diseases
- Emerging therapeutic approaches and potential pharmacological targets
- Original contributions and review articles from international research groups
Journal presentation:
Name: Cells
Publisher: MDPI
Impact Factor (IF): 5.2
Quartile: Q1
Scope: Cell biology, molecular biology, immunology, neuroscience, genetics, biochemistry
Peer review type: Rigorous, single-blind
Indexing: Scopus, Web of Science, PubMed, etc.
Guest Editors
Dr. Gaetano Spinelli & Dr. Francesco Di Blasi
Institute for Biomedical Research and Innovation (IRIB) – National Research Council (CNR), Palermo
Manuscript submission deadline: 1 August 2026
All information about the Special Issue is available at:
https://www.mdpi.com/si/267081