Dr Margherita Stefania Rodolico

Technologist

Margherita Stefania Rodolico (Catania, 1965) graduated in Medicine and Surgery at the University of Catania in 1989 with the thesis entitled "Electroencephalographic, ultra structural and biochemical alterations after a portacaval shunt in the rat. Experimental research ".
She specialized in General Surgery at the University of Catania in 1994 and obtained the title of PhD in Experimental Surgery and Microsurgery at the University of Pavia in 2000.
She received a biennial research grant from the University of Catania (2 November 2001 to 31 October 2003) for the scientific-disciplinary sector F08A "General Surgery".
Since November 2003 she has held the position of III level Technologist at the Institute of Neurological Sciences (ISN) located in Catania, now the Institute for Biomedical Research and Innovation (IRIB) of the National Research Council.
She has been interested in the early characterization and differential diagnosis of nervous system disorders (Parkinson’s disease-parkinsonism) by using the qualitative and quantitative analysis of the nerve fibers in the tissue samples (skin-mucosa).
Since 2009 she took part in a multidisciplinary study on Fabry disease and coordinates the multidisciplinary team of specialists working at the Polyclinic of the University of Catania focused on studying patients with Fabry disease. In particular, her attention is focused on the genotype / phenotype correlation of certain rare mutations with collaborations at national and international level, on early diagnosis and on the prevention of complications of the disease.
Since 2010 she has been involved in the identification of protein markers in human gliomas and their possible correlation to the degree of tumour malignancy.
Her clinical work is carried out under an agreement between the CNR and the University Hospital of Catania.

Research Activity:
- Early characterization and differential diagnosis of diseases of the nervous system - Early diagnosis and prevention of complications of Fabry disease Identification of protein markers in human gliomas and possible correlation to the degree of tumour malignancy.
-Child abuse and maltreatment: clinical aspects and genetic and epigenetic linkages.DSB.AD005.011 -Clinical, genetic and metabolic linkages of childhood neurological disorders.DSB.AD005.011.003